Improved effects of honokiol on temozolomide-induced autophagy and apoptosis of drug-sensitive and -tolerant glioma cells

BACKGROUND: Temozolomide (TMZ)-induced side effects and drug tolerance to human gliomas are still challenging issues now. Our previous studies showed that honokiol, a major bioactive constituent of Magnolia officinalis (Houpo), is safe for normal brain cells and can kill human glioma cells. This stu...

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Bibliografiske detaljer
Udgivet i:BMC Cancer
Main Authors: Chio, Chung-Ching, Chen, Kung-Yen, Chang, Cheng-Kuei, Chuang, Jian-Ying, Liu, Chih-Chung, Liu, Shing-Hwa, Chen, Ruei-Ming
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883267/
https://ncbi.nlm.nih.gov/pubmed/29614990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4267-z
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