Theoretical and NMR Conformational Studies of β-Proline Oligopeptides With Alternating Chirality of Pyrrolidine Units

Synthetic β-peptides are potential functional mimetics of native α-proteins. A recently developed, novel, synthetic approach provides an effective route to the broad group of β-proline oligomers with alternating patterns of stereogenic centers. Conformation of the pyrrolidine ring, Z/E isomerism of...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Mantsyzov, Alexey B., Savelyev, Oleg Y., Ivantcova, Polina M., Bräse, Stefan, Kudryavtsev, Konstantin V., Polshakov, Vladimir I.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883087/
https://ncbi.nlm.nih.gov/pubmed/29644215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00091
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