TAGLN2 polymerizes G-actin in a low ionic state but blocks Arp2/3-nucleated actin branching in physiological conditions

TAGLN is an actin-binding protein family that comprises three isoforms with theorized roles in smooth muscle differentiation, tumour development, lymphocyte activation, and brain chemistry. However, their fundamental characteristics in regulation of the actin-based cytoskeleton are not fully underst...

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Publicat a:Sci Rep
Autors principals: Kim, Hye-Ran, Kwon, Min-Sung, Lee, Sangmin, Mun, YeVin, Lee, Kyung-Sik, Kim, Chang-Hyun, Na, Bo-Ra, Kim, Bit Na Rae, Piragyte, Indre, Lee, Hyun-Su, Jun, Youngsoo, Jin, Mi Sun, Hyun, Young-Min, Jung, Hyun Suk, Mun, Ji Young, Jun, Chang-Duk
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883021/
https://ncbi.nlm.nih.gov/pubmed/29615809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23816-2
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