Morphometric analysis of spread platelets identifies integrin α(IIb)β(3)-specific contractile phenotype

Haemostatic platelet function is intimately linked to cellular mechanics and cytoskeletal morphology. How cytoskeletal reorganizations give rise to a highly contractile phenotype that is necessary for clot contraction remains poorly understood. To elucidate this process in vitro, we developed a morp...

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Vydáno v:Sci Rep
Hlavní autoři: Lickert, Sebastian, Sorrentino, Simona, Studt, Jan-Dirk, Medalia, Ohad, Vogel, Viola, Schoen, Ingmar
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882949/
https://ncbi.nlm.nih.gov/pubmed/29615672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23684-w
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