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Low testosterone in ApoE/LDL receptor double-knockout mice is associated with rarefied testicular capillaries together with fewer and smaller Leydig cells

The testis as a site for atherosclerotic changes has so far attracted little attention. We used the apolipoprotein E (ApoE)/low density lipoprotein (LDL) receptor deficient mouse model (KO) for atherosclerosis (20, 40, 60 and 87-week-old) to investigate whether Leydig cells or the capillary network...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Steinfeld, Kai, Beyer, Daniela, Mühlfeld, Christian, Mietens, Andrea, Eichner, Gerrit, Altinkilic, Bora, Kampschulte, Marian, Jiang, Qingkui, Krombach, Gabriele A., Linn, Thomas, Weidner, Wolfgang, Middendorff, Ralf
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882941/
https://ncbi.nlm.nih.gov/pubmed/29615651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23631-9
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