Structure-function analysis and therapeutic efficacy of antibodies to fungal melanin for melanoma radioimmunotherapy

Metastatic melanoma remains difficult to treat despite recent approvals of several new drugs. Recently we reported encouraging results of Phase I clinical trial of radiolabeled with (188)Re murine monoclonal IgM 6D2 to melanin in patients with Stage III/IV melanoma. Subsequently we generated a novel...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Nosanchuk, J. D., Jeyakumar, A., Ray, A., Revskaya, E., Jiang, Z., Bryan, R. A., Allen, K. J. H., Jiao, R., Malo, M. E., Gómez, B. L., Morgenstern, A., Bruchertseifer, F., Rickles, D., Thornton, G. B., Bowen, A., Casadevall, A., Dadachova, E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882926/
https://ncbi.nlm.nih.gov/pubmed/29615812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23889-z
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