Long-term Western diet fed apolipoprotein E-deficient rats exhibit only modest early atherosclerotic characteristics

In the apolipoprotein E–deficient mouse, the gut microbiota has an impact on the development of atherosclerosis, but whether such correlations are also present in rats requires investigation. Therefore, we studied female SD-Apoe(tm1sage) (Apoe(−/−)) rats fed either a Western diet or a low-fat contro...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Rune, Ida, Rolin, Bidda, Lykkesfeldt, Jens, Nielsen, Dennis Sandris, Krych, Łukasz, Kanter, Jenny E., Bornfeldt, Karin E., Kihl, Pernille, Buschard, Karsten, Josefsen, Knud, Fels, Johannes Josef, Mortensen, Alan, Christoffersen, Berit, Kirk, Rikke Kaae, Hansen, Axel Kornerup
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882891/
https://ncbi.nlm.nih.gov/pubmed/29615808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23835-z
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