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PDZ domain-binding motif of Tax sustains T-cell proliferation in HTLV-1-infected humanized mice
Human T-cell leukemia virus type 1 (HTLV-1) is the etiological agent of adult T-cell leukemia/lymphoma (ATLL), an aggressive malignant proliferation of activated CD4+ T lymphocytes. The viral Tax oncoprotein is critically involved in both HTLV-1-replication and T-cell proliferation, a prerequisite t...
שמור ב:
| הוצא לאור ב: | PLoS Pathog |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5882172/ https://ncbi.nlm.nih.gov/pubmed/29566098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006933 |
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