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Targeting dysfunctional beta-cell signaling for the potential treatment of type 1 diabetes mellitus

Since its discovery and purification by Frederick Banting in 1921, exogenous insulin has remained almost the sole therapy for type 1 diabetes mellitus. While insulin alleviates the primary dysfunction of the disease, many other aspects of the pathophysiology of type 1 diabetes mellitus are unaffecte...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Exp Biol Med (Maywood)
Prif Awduron: Fenske, Rachel J, Kimple, Michelle E
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: SAGE Publications 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882023/
https://ncbi.nlm.nih.gov/pubmed/29504478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370218761662
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