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Current understanding and future perspectives of the roles of sirtuins in the reprogramming and differentiation of pluripotent stem cells
In mammalian cells, there are seven members of the sirtuin protein family (SIRT1–7). SIRT1, SIRT6, and SIRT7 catalyze posttranslational modification of proteins in the nucleus, SIRT3, SIRT4, and SIRT5 are in the mitochondria and SIRT2 is in the cytosol. SIRT1 can deacetylate the transcription factor...
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| Publicado no: | Exp Biol Med (Maywood) |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5882022/ https://ncbi.nlm.nih.gov/pubmed/29557214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370218759636 |
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