Subtherapeutic concentrations of infliximab and adalimumab are associated with increased disease activity in Crohn’s disease

BACKGROUND: Low anti-tumor necrosis factor α (TNFα) serum concentrations may result in lack of treatment response in patients with inflammatory bowel disease. We determined the anti-TNFα drug concentrations in patients with inflammatory bowel disease and investigated whether or not subtherapeutic dr...

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Detalhes bibliográficos
Publicado no:Therap Adv Gastroenterol
Main Authors: Carlsen, Arne, Omdal, Roald, Leitao, Kristian Øgreid, Isaksen, Kjetil, Hetta, Anne Kristine, Karlsen, Lars Normann, Aabakken, Lars, Bolstad, Nils, Warren, David, Lundin, Knut E.A., Grimstad, Tore
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881967/
https://ncbi.nlm.nih.gov/pubmed/29623105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756284818759930
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