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Epigenetic and post-transcriptional regulation of CD16 expression during human natural killer cell development()

The surface receptor FcγRIIIA (CD16a) is encoded by the FCGR3A gene and is acquired by human natural killer (NK) cells during maturation. NK cells bind the Fc portion of IgG via CD16a, and execute antibody-dependent cellular cytotoxicity, which is critical for the effectiveness of several anti-tumor...

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Detalhes bibliográficos
Publicado no:J Immunol
Principais autores: Victor, Aaron R., Weigel, Christoph, Scoville, Steven D., Chan, Wing Keung, Chatman, Kelsey, Nemer, Mary M., Mao, Charlene, Young, Karen A., Zhang, Jianying, Yu, Jianhua, Freud, Aharon G., Oakes, Christopher C., Caligiuri, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881939/
https://ncbi.nlm.nih.gov/pubmed/29229679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701128
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