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The Structure-Forming Juncture in Oxidative Protein Folding: What happens in the ER?

The folding of disulfide bond containing proteins proceeds in a two-fold manner. Initially, cysteines are oxidized to form disulfide bonds. Structure is largely absent in this period. Next, when a minimally correct number of native linkages of disulfide bonds have been acquired, the biopolymer confo...

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Dettagli Bibliografici
Pubblicato in:Adv Exp Med Biol
Autore principale: Narayan, Mahesh
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881899/
https://ncbi.nlm.nih.gov/pubmed/28815511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/5584_2017_88
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