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hTERT peptide fragment GV1001 demonstrates radioprotective and antifibrotic effects through suppression of TGF-β signaling
GV1001 is a 16-amino acid peptide derived from the human telomerase reverse transcriptase (hTERT) protein (616–626; EARPALLTSRLRFIPK), which lies within the reverse transcriptase domain. Originally developed as an anticancer vaccine, GV1001 demonstrates diverse cellular effects, including anti-infla...
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| Pubblicato in: | Int J Mol Med |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
D.A. Spandidos
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5881842/ https://ncbi.nlm.nih.gov/pubmed/29568955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3566 |
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