Synthesis and characterization of heparosan-granulocyte-colony stimulating factor conjugates: a natural sugar-based drug delivery system to treat neutropenia

Many injectable drugs require delivery strategies for enhancing their pharmacokinetics due to rapid loss via renal filtration if possess low molecular weight (<60–70 kDa) and/or clearance by the body's components (e.g., proteases, antibodies, high-efficiency receptors) in their native form....

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Glycobiology
Päätekijät: Jing, Wei, Roberts, Jonathan W, Green, Dixy E, Almond, Andrew, DeAngelis, Paul L
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2017
Aiheet:
Regular Manuscripts
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881802/
https://ncbi.nlm.nih.gov/pubmed/28973394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwx072
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