Expression of Ecto-nucleoside Triphosphate Diphosphohydrolases-2 and -3 in the Enteric Nervous System Affects Inflammation in Experimental Colitis and Crohn’s Disease

OBJECTIVE: Recent studies have suggested that the enteric nervous system can modulate gut immunity. Ecto-nucleoside triphosphate diphosphohydrolases [E-NTPDases] regulate purinergic signalling by sequential phosphohydrolysis of pro-inflammatory extracellular adenosine 5'-triphosphate [ATP]. Her...

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Dettagli Bibliografici
Pubblicato in:J Crohns Colitis
Autori principali: Feldbrügge, Linda, Moss, Alan C, Yee, Eric U, Csizmadia, Eva, Mitsuhashi, Shuji, Longhi, Maria Serena, Sandhu, Bynvant, Stephan, Holger, Wu, Yan, Cheifetz, Adam S, Müller, Christa E, Sévigny, Jean, Robson, Simon C, Jiang, Z Gordon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881706/
https://ncbi.nlm.nih.gov/pubmed/28472257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecco-jcc/jjx058
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