The Pathogenic Role of NLRP3 Inflammasome Activation in Inflammatory Bowel Diseases of Both Mice and Humans

BACKGROUND AND AIMS: NLRP3 inflammasome is known to be involved in inflammatory bowel diseases. However, it is controversial whether it is pathogenic or beneficial. This study evaluated the roles of NLRP3 inflammasome in the pathogenesis of inflammatory bowel disease in IL-10(-/-) mice and humans. M...

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Publicado en:J Crohns Colitis
Autores principales: Liu, Ling, Dong, Ying, Ye, Mei, Jin, Shi, Yang, Jianbo, Joosse, Maria E., Sun, Yu, Zhang, Jennifer, Lazarev, Mark, Brant, Steven R., Safar, Bashar, Marohn, Michael, Mezey, Esteban, Li, Xuhang
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881697/
https://ncbi.nlm.nih.gov/pubmed/27993998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecco-jcc/jjw219
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