The Pathogenic Role of NLRP3 Inflammasome Activation in Inflammatory Bowel Diseases of Both Mice and Humans

BACKGROUND AND AIMS: NLRP3 inflammasome is known to be involved in inflammatory bowel diseases. However, it is controversial whether it is pathogenic or beneficial. This study evaluated the roles of NLRP3 inflammasome in the pathogenesis of inflammatory bowel disease in IL-10(-/-) mice and humans. M...

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Vydáno v:J Crohns Colitis
Hlavní autoři: Liu, Ling, Dong, Ying, Ye, Mei, Jin, Shi, Yang, Jianbo, Joosse, Maria E., Sun, Yu, Zhang, Jennifer, Lazarev, Mark, Brant, Steven R., Safar, Bashar, Marohn, Michael, Mezey, Esteban, Li, Xuhang
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881697/
https://ncbi.nlm.nih.gov/pubmed/27993998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecco-jcc/jjw219
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