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Inhibition effects of total flavonoids from Scutellaria barbata D. Don on human breast carcinoma bone metastasis via downregulating PTHrP pathway

It is abundantly clear that tumor-derived parathyroid hormone-related protein (PTHrP), receptor activator of nuclear factor-κB ligand (RANKL) and osteoprotegerin (OPG) are central contributors in promoting osteolytic process of breast carcinoma bone metastasis. Forcusing on this molecular basis, the...

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發表在:Int J Mol Med
Main Authors: Zheng, Xiao, Kang, Wen, Liu, Huihui, Guo, Shanyu
格式: Artigo
語言:Inglês
出版: D.A. Spandidos 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881663/
https://ncbi.nlm.nih.gov/pubmed/29512770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3515
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