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Transmission of integrin β7 transmembrane domain topology enables gut lymphoid tissue development
Integrin activation regulates adhesion, extracellular matrix assembly, and cell migration, thereby playing an indispensable role in development and in many pathological processes. A proline mutation in the central integrin β3 transmembrane domain (TMD) creates a flexible kink that uncouples the topo...
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| Gepubliceerd in: | J Cell Biol |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Rockefeller University Press
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5881498/ https://ncbi.nlm.nih.gov/pubmed/29535192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201707055 |
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