Transmission of integrin β7 transmembrane domain topology enables gut lymphoid tissue development

Integrin activation regulates adhesion, extracellular matrix assembly, and cell migration, thereby playing an indispensable role in development and in many pathological processes. A proline mutation in the central integrin β3 transmembrane domain (TMD) creates a flexible kink that uncouples the topo...

Full description

Saved in:
Bibliographic Details
Published in:J Cell Biol
Main Authors: Sun, Hao, Lagarrigue, Frederic, Gingras, Alexandre R., Fan, Zhichao, Ley, Klaus, Ginsberg, Mark H.
Format: Artigo
Language:Inglês
Published: Rockefeller University Press 2018
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881498/
https://ncbi.nlm.nih.gov/pubmed/29535192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201707055
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items