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Transmission of integrin β7 transmembrane domain topology enables gut lymphoid tissue development

Integrin activation regulates adhesion, extracellular matrix assembly, and cell migration, thereby playing an indispensable role in development and in many pathological processes. A proline mutation in the central integrin β3 transmembrane domain (TMD) creates a flexible kink that uncouples the topo...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Sun, Hao, Lagarrigue, Frederic, Gingras, Alexandre R., Fan, Zhichao, Ley, Klaus, Ginsberg, Mark H.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881498/
https://ncbi.nlm.nih.gov/pubmed/29535192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201707055
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