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Centrobin controls primary ciliogenesis in vertebrates
The BRCA2 interactor, centrobin, is a centrosomal protein that has been implicated in centriole duplication and microtubule stability. We used genome editing to ablate CNTROB in hTERT-RPE1 cells and observed an increased frequency of monocentriolar and acentriolar cells. Using a novel monoclonal ant...
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| Pubblicato in: | J Cell Biol |
|---|---|
| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Rockefeller University Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5881496/ https://ncbi.nlm.nih.gov/pubmed/29440264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201706095 |
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