IL-7–dependent maintenance of ILC3s is required for normal entry of lymphocytes into lymph nodes

IL-7 is essential for the development and homeostasis of T and B lymphocytes and is critical for neonatal lymph node organogenesis because Il7(−/−) mice lack normal lymph nodes. Whether IL-7 is a continued requirement for normal lymph node structure and function is unknown. To address this, we ablat...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Exp Med
Auteurs principaux: Yang, Jie, Cornelissen, Ferry, Papazian, Natalie, Reijmers, Rogier M., Llorian, Miriam, Cupedo, Tom, Coles, Mark, Seddon, Benedict
Format: Artigo
Langue:Inglês
Publié: Rockefeller University Press 2018
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881462/
https://ncbi.nlm.nih.gov/pubmed/29472496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170518
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