Isomangiferin, a Novel Potent Vascular Endothelial Growth Factor Receptor 2 Kinase Inhibitor, Suppresses Breast Cancer Growth, Metastasis and Angiogenesis

PURPOSE: Vascular endothelial growth factor (VEGF) signal transduction mainly depends on its binding to VEGF receptor 2 (VEGFR-2). VEGF downstream signaling proteins mediate several of its effects in cancer progression, including those on tumor growth, metastasis, and blood vessel formation. The act...

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Detalhes bibliográficos
Publicado no:J Breast Cancer
Main Authors: Wang, Banghua, Shen, Jia, Wang, Zexia, Liu, Jianxia, Ning, Zhifeng, Hu, Meichun
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Breast Cancer Society 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880961/
https://ncbi.nlm.nih.gov/pubmed/29628979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4048/jbc.2018.21.1.11
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