Reduction of Proliferating Olfactory Cells and Low Expression of Extracellular Matrix Genes Are Hallmarks of the Aged Olfactory Mucosa

Background: The incidence of olfactory impairment increases with age; however, the detailed molecular and cellular mechanisms underlying this increase are yet to be determined. Methods: We examined the influence of aging on olfactory receptor neurons (ORNs), which are maintained by a unique stem cel...

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Vydáno v:Front Aging Neurosci
Hlavní autoři: Ueha, Rumi, Shichino, Shigeyuki, Ueha, Satoshi, Kondo, Kenji, Kikuta, Shu, Nishijima, Hironobu, Matsushima, Kouji, Yamasoba, Tatsuya
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880952/
https://ncbi.nlm.nih.gov/pubmed/29636678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00086
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