Genomic profiling of dedifferentiated liposarcoma compared to matched well-differentiated liposarcoma reveals higher genomic complexity and a common origin

Well-differentiated (WD) liposarcoma is a low-grade mesenchymal tumor with features of mature adipocytes and high propensity for local recurrence. Often, WD patients present with or later progress to a higher-grade nonlipogenic form known as dedifferentiated (DD) liposarcoma. These DD tumors behave...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Mol Case Stud
Main Authors: Beird, Hannah C., Wu, Chia-Chin, Ingram, Davis R., Wang, Wei-Lien, Alimohamed, Asrar, Gumbs, Curtis, Little, Latasha, Song, Xingzhi, Feig, Barry W., Roland, Christina L., Zhang, Jianhua, Benjamin, Robert S., Hwu, Patrick, Lazar, Alexander J., Futreal, P. Andrew, Somaiah, Neeta
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880260/
https://ncbi.nlm.nih.gov/pubmed/29610390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a002386
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