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Obesity and outcome of post-menopausal women receiving adjuvant letrozole for breast cancer

INTRODUCTION: Aromatase enzyme activity is predominant in adipose tissue. This has led to speculation that aromatase activity is elevated in obese women and subsequently decreased the clinical activity of adjuvant aromatase inhibitors (AIs) in women with estrogen receptor positive (ER+) breast cance...

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Podrobná bibliografie
Vydáno v:Ecancermedicalscience
Hlavní autoři: Zekri, Jamal, Farag, Kamel, Allithy, Ahmed
Médium: Artigo
Jazyk:Inglês
Vydáno: Cancer Intelligence 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880223/
https://ncbi.nlm.nih.gov/pubmed/29662534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3332/ecancer.2018.821
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