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Obesity and outcome of post-menopausal women receiving adjuvant letrozole for breast cancer

INTRODUCTION: Aromatase enzyme activity is predominant in adipose tissue. This has led to speculation that aromatase activity is elevated in obese women and subsequently decreased the clinical activity of adjuvant aromatase inhibitors (AIs) in women with estrogen receptor positive (ER+) breast cance...

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Detalhes bibliográficos
Publicado no:Ecancermedicalscience
Main Authors: Zekri, Jamal, Farag, Kamel, Allithy, Ahmed
Formato: Artigo
Idioma:Inglês
Publicado em: Cancer Intelligence 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880223/
https://ncbi.nlm.nih.gov/pubmed/29662534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3332/ecancer.2018.821
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