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Bone Morphogenetic Protein–Based Therapeutic Approaches

Bone morphogenetic proteins (BMPs) constitute the largest subdivision of the transforming growth factor (TGF)-β family of ligands and exert most of their effects through the canonical effectors Smad1, 5, and 8. Appropriate regulation of BMP signaling is critical for the development and homeostasis o...

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Bibliografiske detaljer
Udgivet i:Cold Spring Harb Perspect Biol
Main Authors: Lowery, Jonathan W., Rosen, Vicki
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880173/
https://ncbi.nlm.nih.gov/pubmed/28389444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a022327
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