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Taking a position on intramembrane proteolysis

Decades of work have contributed to our in-depth mechanistic understanding of soluble proteases, but much less is known about the catalytic mechanism of intramembrane proteolysis due to inherent difficulties in both preparing and analyzing integral membrane enzymes and transmembrane substrates. New...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autor principal: Lemieux, M. Joanne
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880146/
https://ncbi.nlm.nih.gov/pubmed/29602877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H118.002210
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