Does tranexamic acid lead to changes in MRI measures of brain tissue health in patients with spontaneous intracerebral haemorrhage? Protocol for a MRI substudy nested within the double-blind randomised controlled TICH-2 trial

OBJECTIVES: To test whether administration of the antifibrinolytic drug tranexamic acid (TXA) in patients with spontaneous intracerebral haemorrhage (SICH) leads to increased prevalence of diffusion-weighted MRI-defined hyperintense ischaemic lesions (primary hypothesis) or reduced perihaematomal oe...

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Опубликовано в: :BMJ Open
Главные авторы: Dineen, Rob A, Pszczolkowski, Stefan, Flaherty, Katie, Law, Zhe K, Morgan, Paul S, Roberts, Ian, Werring, David J, Al-Shahi Salman, Rustam, England, Tim, Bath, Philip M, Sprigg, Nikola
Формат: Artigo
Язык:Inglês
Опубликовано: BMJ Publishing Group 2018
Предметы:
Radiology and Imaging
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879748/
https://ncbi.nlm.nih.gov/pubmed/29431141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2017-019930
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