Decitabine Inhibits Gamma Delta T Cell Cytotoxicity by Promoting KIR2DL2/3 Expression

Gamma delta (γδ) T cells, which possess potent cytotoxicity against a wide range of cancer cells, have become a potential avenue for adoptive immunotherapy. Decitabine (DAC) has been reported to enhance the immunogenicity of tumor cells, thereby reinstating endogenous immune recognition and tumor ly...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Niu, Chao, Li, Min, Zhu, Shan, Chen, Yongchong, Zhou, Lei, Xu, Dongsheng, Li, Wei, Cui, Jiuwei, Liu, Yongjun, Chen, Jingtao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879086/
https://ncbi.nlm.nih.gov/pubmed/29632540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00617
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