Selective IKK2 inhibitor IMD0354 disrupts NF-κB signaling to suppress corneal inflammation and angiogenesis

Corneal neovascularization is a sight-threatening condition caused by angiogenesis in the normally avascular cornea. Neovascularization of the cornea is often associated with an inflammatory response, thus targeting VEGF-A alone yields only a limited efficacy. The NF-κB signaling pathway plays impor...

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Detalhes bibliográficos
Publicado no:Angiogenesis
Main Authors: Lennikov, Anton, Mirabelli, Pierfrancesco, Mukwaya, Anthony, Schaupper, Mira, Thangavelu, Muthukumar, Lachota, Mieszko, Ali, Zaheer, Jensen, Lasse, Lagali, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2018
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5878206/
https://ncbi.nlm.nih.gov/pubmed/29332242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-018-9594-9
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