Platelet function is disturbed by the angiogenesis inhibitors sunitinib and sorafenib, but unaffected by bevacizumab

INTRODUCTION: At the clinical introduction of antiangiogenic agents as anticancer agents, no major toxicities were expected as merely just endothelial cells (ECs) in tumors would be affected. However, several (serious) toxicities became apparent, of which underlying mechanisms are largely unknown. W...

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Detalhes bibliográficos
Publicado no:Angiogenesis
Main Authors: Walraven, Maudy, Homs, Marjolein Y. V., van der Veldt, Astrid A. M., Dekker, Henk, Koldenhof, Jose, Honeywell, Richard, Barendrecht, Arjan, Sebastian, Silvie A. E., Parr, Naomi, Koekman, Arnold C., Voest, Emile E., Roest, Mark, Korporaal, Suzanne J. A., Verheul, Henk M. W.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2018
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5878190/
https://ncbi.nlm.nih.gov/pubmed/29532289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-018-9598-5
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