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Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes
AIMS/HYPOTHESIS: Improved biomarkers are acutely needed for the detection of developing type 1 diabetes, prior to critical loss of beta cell mass. We previously demonstrated that elevated beta cell microRNA 21 (miR-21-5p) in rodent and human models of type 1 diabetes increased beta cell apoptosis. W...
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Publicado no: | Diabetologia |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5878132/ https://ncbi.nlm.nih.gov/pubmed/29445851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-018-4559-5 |
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