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DESIGN OF VACCINE TRIALS DURING OUTBREAKS WITH AND WITHOUT A DELAYED VACCINATION COMPARATOR

Conducting vaccine efficacy trials during outbreaks of emerging pathogens poses particular challenges. The “Ebola ça suffit” trial in Guinea used a novel ring vaccination cluster randomized design to target populations at highest risk of infection. Another key feature of the trial was the use of a d...

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Vydáno v:Ann Appl Stat
Hlavní autoři: Dean, Natalie E., Halloran, M. Elizabeth, Longini, Ira M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5878056/
https://ncbi.nlm.nih.gov/pubmed/29606991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1214/17-AOAS1095
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