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Select and resequence reveals relative fitness of bacteria in symbiotic and free-living environments

Assays to accurately estimate relative fitness of bacteria growing in multistrain communities can advance our understanding of how selection shapes diversity within a lineage. Here, we present a variant of the “evolve and resequence” approach both to estimate relative fitness and to identify genetic...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Burghardt, Liana T., Epstein, Brendan, Guhlin, Joseph, Nelson, Matt S., Taylor, Margaret R., Young, Nevin D., Sadowsky, Michael J., Tiffin, Peter
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877963/
https://ncbi.nlm.nih.gov/pubmed/29453274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714246115
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