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Robo and Ror function in a common receptor complex to regulate Wnt-mediated neurite outgrowth in Caenorhabditis elegans

Growing axons are exposed to various guidance cues en route to their targets, but the mechanisms that govern the response of growth cones to combinations of signals remain largely elusive. Here, we found that the sole Robo receptor, SAX-3, in Caenorhabditis elegans functions as a coreceptor for Wnt/...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Wang, Jiaming, Ding, Mei
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877952/
https://ncbi.nlm.nih.gov/pubmed/29463707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1717468115
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