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Synthesis of a novel fused pyrrolodiazepine-based library with anti-cancer activity

Development of drugs for new and persistent diseases will increasingly rely on the expansion of accessible chemical space to allow exploration of novel molecular targets. Here we report the synthesis of a library of novel fused heterobicyclic small molecules based on the 1,4-diazepine and 2,4-pyrrol...

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Detalhes bibliográficos
Publicado no:Tetrahedron Lett
Main Authors: Malik, Neha, Iyamu, Iredia D., Scheidt, Karl A., Schiltz, Gary E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877814/
https://ncbi.nlm.nih.gov/pubmed/29610541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2018.03.021
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