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Functional and evolutionary implications of gene orthology

Orthologues and paralogues are types of homologous genes that are related by speciation or duplication, respectively. Orthologous genes are generally assumed to retain equivalent functions in different organisms and to share other key properties. Several recent comparative genomic studies have focus...

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Pubblicato in:Nat Rev Genet
Autori principali: Gabaldón, Toni, Koonin, Eugene V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877793/
https://ncbi.nlm.nih.gov/pubmed/23552219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg3456
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