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Exploring the In Vivo Anti-Inflammatory Actions of Simvastatin-Loaded Porous Microspheres on Inflamed Tenocytes in a Collagenase-Induced Animal Model of Achilles Tendinitis

Tendon rupture induces an inflammatory response characterized by release of pro-inflammatory cytokines and impaired tendon performance. This study sought to investigate the therapeutic effects of simvastatin-loaded porous microspheres (SIM/PMSs) on inflamed tenocytes in vitro and collagenase-induced...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Jeong, Chandong, Kim, Sung Eun, Shim, Kyu-Sik, Kim, Hak-Jun, Song, Mi Hyun, Park, Kyeongsoon, Song, Hae-Ryong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877681/
https://ncbi.nlm.nih.gov/pubmed/29534523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19030820
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