Regulation of T-Cell Signaling by Post-Translational Modifications in Autoimmune Disease

The adaptive immune system involves antigen-specific host defense mechanisms mediated by T and B cells. In particular, CD4(+) T cells play a central role in the elimination of pathogens. Immunological tolerance in the thymus regulates T lymphocytes to avoid self-components, including induction of ce...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Kuwabara, Taku, Matsui, Yukihide, Ishikawa, Fumio, Kondo, Motonari
Format: Artigo
Language:Inglês
Published: MDPI 2018
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877680/
https://ncbi.nlm.nih.gov/pubmed/29534522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19030819
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