The Role of mTOR in Neuroendocrine Tumors: Future Cornerstone of a Winning Strategy?

The mechanistic target of rapamycin (mTOR) is part of the phosphoinositide-3-kinase (PI3K)/protein kinase B (AkT)/mTOR pathway and owes its name to the inhibitory effect of rapamycin. The mTOR has a central converging role for many cell functions, serving as a sensor for extracellular signals from e...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Lamberti, Giuseppe, Brighi, Nicole, Maggio, Ilaria, Manuzzi, Lisa, Peterle, Chiara, Ambrosini, Valentina, Ricci, Claudio, Casadei, Riccardo, Campana, Davide
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877608/
https://ncbi.nlm.nih.gov/pubmed/29509701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19030747
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