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Reaction Intermediates in the Heme Degradation Reaction by HutZ from Vibrio cholerae

HutZ is a heme-degrading enzyme in Vibrio cholerae. It converts heme to biliverdin via verdoheme, suggesting that it follows the same reaction mechanism as that of mammalian heme oxygenase. However, none of the key intermediates have been identified. In this study, we applied steady-state and time-r...

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Détails bibliographiques
Publié dans:Dalton Trans
Auteurs principaux: Uchida, Takeshi, Sekine, Yukari, Dojun, Nobuhiko, Lewis-Ballester, Ariel, Ishigami, Izumi, Matsui, Toshitaka, Yeh, Syun-Ru, Ishimori, Koichiro
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5876723/
https://ncbi.nlm.nih.gov/pubmed/28607990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7dt01562c
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