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Reaction Intermediates in the Heme Degradation Reaction by HutZ from Vibrio cholerae

HutZ is a heme-degrading enzyme in Vibrio cholerae. It converts heme to biliverdin via verdoheme, suggesting that it follows the same reaction mechanism as that of mammalian heme oxygenase. However, none of the key intermediates have been identified. In this study, we applied steady-state and time-r...

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Publicat a:Dalton Trans
Autors principals: Uchida, Takeshi, Sekine, Yukari, Dojun, Nobuhiko, Lewis-Ballester, Ariel, Ishigami, Izumi, Matsui, Toshitaka, Yeh, Syun-Ru, Ishimori, Koichiro
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5876723/
https://ncbi.nlm.nih.gov/pubmed/28607990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7dt01562c
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