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Reaction Intermediates in the Heme Degradation Reaction by HutZ from Vibrio cholerae

HutZ is a heme-degrading enzyme in Vibrio cholerae. It converts heme to biliverdin via verdoheme, suggesting that it follows the same reaction mechanism as that of mammalian heme oxygenase. However, none of the key intermediates have been identified. In this study, we applied steady-state and time-r...

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Publicado en:Dalton Trans
Main Authors: Uchida, Takeshi, Sekine, Yukari, Dojun, Nobuhiko, Lewis-Ballester, Ariel, Ishigami, Izumi, Matsui, Toshitaka, Yeh, Syun-Ru, Ishimori, Koichiro
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5876723/
https://ncbi.nlm.nih.gov/pubmed/28607990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7dt01562c
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