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A network modeling approach to elucidate drug resistance mechanisms and predict combinatorial drug treatments in breast cancer

BACKGROUND: Mechanistic models of within-cell signal transduction networks can explain how these networks integrate internal and external inputs to give rise to the appropriate cellular response. These models can be fruitfully used in cancer cells, whose aberrant decision-making regarding their surv...

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Detalhes bibliográficos
Publicado no:Cancer Converg
Main Authors: Gómez Tejeda Zañudo, Jorge, Scaltriti, Maurizio, Albert, Réka
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5876695/
https://ncbi.nlm.nih.gov/pubmed/29623959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41236-017-0007-6
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