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Functional cyclophilin D moderates platelet adhesion, but enhances the lytic resistance of fibrin

In the course of thrombosis, platelets are exposed to a variety of activating stimuli classified as ‘strong’ (e.g. thrombin and collagen) or ‘mild’ (e.g. ADP). In response, activated platelets adhere to injured vasculature, aggregate, and stabilise the three-dimensional fibrin scaffold of the expand...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Varjú, Imre, Farkas, Veronika Judit, Kőhidai, László, Szabó, László, Farkas, Ádám Zoltán, Polgár, Lívia, Chinopoulos, Christos, Kolev, Krasimir
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5876378/
https://ncbi.nlm.nih.gov/pubmed/29599453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23725-4
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