Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome

Hutchinson-Gilford progeria syndrome (HGPS) and Werner syndrome (WS) are two of the best characterized human progeroid syndromes. HGPS is caused by a point mutation in lamin A (LMNA) gene, resulting in the production of a truncated protein product—progerin. WS is caused by mutations in WRN gene, enc...

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Udgivet i:Protein Cell
Main Authors: Wu, Zeming, Zhang, Weiqi, Song, Moshi, Wang, Wei, Wei, Gang, Li, Wei, Lei, Jinghui, Huang, Yu, Sang, Yanmei, Chan, Piu, Chen, Chang, Qu, Jing, Suzuki, Keiichiro, Belmonte, Juan Carlos Izpisua, Liu, Guang-Hui
Format: Artigo
Sprog:Inglês
Udgivet: Higher Education Press 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5876188/
https://ncbi.nlm.nih.gov/pubmed/29476423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-018-0517-8
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