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An empirical likelihood ratio test robust to individual heterogeneity for differential expression analysis of RNA-seq

The individual sample heterogeneity is one of the biggest obstacles in biomarker identification for complex diseases such as cancers. Current statistical models to identify differentially expressed genes between disease and control groups often overlook the substantial human sample heterogeneity. Me...

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Detalhes bibliográficos
Publicado no:Brief Bioinform
Main Authors: Xu, Maoqi, Chen, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875907/
https://ncbi.nlm.nih.gov/pubmed/27769992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbw103
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