Pluripotency gene network dynamics: System views from parametric analysis

Multiple experimental data demonstrated that the core gene network orchestrating self-renewal and differentiation of mouse embryonic stem cells involves activity of Oct4, Sox2 and Nanog genes by means of a number of positive feedback loops among them. However, recent studies indicated that the archi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Akberdin, Ilya R., Omelyanchuk, Nadezda A., Fadeev, Stanislav I., Leskova, Natalya E., Oschepkova, Evgeniya A., Kazantsev, Fedor V., Matushkin, Yury G., Afonnikov, Dmitry A., Kolchanov, Nikolay A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875786/
https://ncbi.nlm.nih.gov/pubmed/29596533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194464
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