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Age-related collagen turnover of the interstitial matrix and basement membrane: Implications of age- and sex-dependent remodeling of the extracellular matrix

The extracellular matrix (ECM) plays a vital role in maintaining normal tissue function. Collagens are major components of the ECM and there is a tight equilibrium between degradation and formation of these proteins ensuring tissue health and homeostasis. As a consequence of tissue turnover, small c...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kehlet, Stephanie N., Willumsen, Nicholas, Armbrecht, Gabriele, Dietzel, Roswitha, Brix, Susanne, Henriksen, Kim, Karsdal, Morten A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875766/
https://ncbi.nlm.nih.gov/pubmed/29596429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194458
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