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Ischemic stroke alters the expression of the transcribed ultraconserved regions of the genome in rat brain

BACKGROUND AND PURPOSE: Human and rodent genomes diverged ~75 million years ago. However, 481 regions of their genomes (200 to 779 nucleotide each) remained absolutely conserved and form noncoding RNAs known as transcribed ultraconserved regions (T-UCRs). The functional significance of T-UCRs is not...

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Bibliographische Detailangaben
Veröffentlicht in:Stroke
Hauptverfasser: Mehta, Suresh L., Vemuganti, Raghu
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875717/
https://ncbi.nlm.nih.gov/pubmed/29581345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.118.020663
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