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Complete, long-lasting protection against malaria of mice primed and boosted with two distinct viral vectors expressing the same plasmodial antigen

We report that complete protection against malaria and total inhibition of liver stage development and parasitemia was obtained in 100% of BALB/c mice primed with a replication-defective recombinant adenovirus expressing the circumsporozoite (CS) protein of Plasmodium yoelii (AdPyCS), followed by a...

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Detalhes bibliográficos
Main Authors: Bruña-Romero, Oscar, González-Aseguinolaza, Gloria, Hafalla, Julius C. R., Tsuji, Moriya, Nussenzweig, Ruth S.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC58757/
https://ncbi.nlm.nih.gov/pubmed/11553779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.191380898
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