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Dual treatment with a fixed ratio of glucagon and insulin increases the therapeutic window of insulin in diabetic rats

The current available insulin therapies decrease blood glucose but are associated with the risk of developing hypoglycemia. Glucagon is a counter regulatory hormone and we hypothesize that a fixed ratio of insulin and a long‐acting glucagon‐analogue can reduce the risk of hypoglycemia. To define an...

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Publicat a:Physiol Rep
Autors principals: Pedersen, Christina, Bouman, Stephan D., Porsgaard, Trine, Rosenkilde, Mette M., Roed, Nikolaj K.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875541/
https://ncbi.nlm.nih.gov/pubmed/29595915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13657
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